PROTON PUMP FUNCTION IN GASTRIC ACID SECRETION

The proton pump contributes a critical role during gastric acid {secretion|. The pump is an integral membrane protein found on the apical membrane of parietal cells in the stomach lining. It catalyzes the active movement of protons (H+) from the cytoplasm of parietal cells into the gastric lumen, resulting to the lowering of the stomach contents.